This enterprise has existed in one form or another since the 70s. At that time, and for a long time after, it was a unique institution--a basic science laboratory in an academic department of emergency medicine. Our mission since that time has remained unchanged:
1. To investigate ischemic brain damage and related disorders, including analysis of the molecular mechanisms of neuronal death and salvage.
2. To contribute to the development of clinically effective therapies for brain ischemia and related disorders.
3. To prepare promising students for careers as scientists, including physician-scientists.
To that end, this laboratory has published dozens of papers, reviews, abstracts and chapters, secured millions of dollars in funding, and mentored many medical students, residents, fellows, and graduate students. As we move forward, we are excited at the prospect of taking some of our hard-won observations into the clinical research arena for investigation of potential therapies.