That's right, I did--and I said it to underscore the
argument that single drug therapy will never work. But here's the deal:
hypothermia is not single therapy!
Like insulin, hypothermia has multiple salutary effects. It
has been shown to:
pro-survival signaling processes--including activation of Akt!
cytochrome c release from mitochondria!
free radical production and propagation!
glutamate receptor composition and activation in ways that are good for
That's one terrific therapeutic package…not single therapy
at all. Cool.