As it happens, Akt doesn't just signal to survival. Akt also
signals to translational control. Although it remains to be demonstrated that insulin
induces eIF2 phosphorylation and rescues protein synthesis in brain ischemia through
Akt, it is certainly a tempting hypothesis. If it turns out to be true,
it puts Akt front and center in the fight to salvage neurons--and we've already
shown that we have a way to turn it on, right off the shelf.