If you weren't thinking about pizza and beer right now, just staring at that animation could get you thinking about a "differential diagnosis" of how protein synthesis gets interrupted after transient global brain ischemia: 

1. All tuckered out. Maybe there's just not enough energy after ischemia to drive the energy-dependent processes of protein synthesis.

2. DNA badness: Maybe DNA is screwed up. Maybe free radicals or turncoat enzymes are going all Braveheart on the DNA after an ischemic insult.

3. Transcription badness: Maybe RNA polymerase is confused, damaged, drunk or dead. No transcription, no mRNA. No mRNA, no new protein.

4. mRNA badness: Maybe mRNA can't be processed correctly, or gets damaged, or fails to get out of the nucleus.

5. Translational badness: Maybe everything else goes ok, but at the last minute the ribosome can't translate the mRNA into protein.

Figure. This cartoon of the overall process of protein synthesis suggests several points at which the process could go wrong...go wrong...go wrong...